姓名：何一燕

性别：女

职称/职务：副教授，南京工业大学材料科学与工程学院高分子系副主任

出生年月：1986年9月

电子邮箱：yiyanhe@njtech.edu.cn

教育背景：

2009.09 – 2014.06 四川大学高分子化学与物理专业博士学位

2005.09 – 2009.06  四川大学高分子化学与物理专业学士学位

工作经历：

2017.06 – 至今   南京工业大学材料科学与工程学院 副教授

2018.11 – 2019.11  新加坡科技研究局 访问学者

2016.03 – 2018.06  四川大学生物医学工程专业博士后

2014.07 – 2017.06  四川大学国家生物医学工程技术研究中心 讲师

研究领域：

 医用高分子

 生物医用材料  

项目：

国家自然科学基金面上项目，31871000，负责人。

国家重点研发计划项目子课题，2017YFC1103501，负责人。

国家自然科学基金青年科学基金项目，31500810，负责人。

中国博士后科学基金面上一等资助，2017M610602，负责人。

南京工业大学引进人才科研启动经费资助项目，39803132，负责人。

四川大学引进人才科研启动经费资助项目，YJ201464，负责人。

四川大学青年教师科研启动基金，2015SCU11038，负责人。

申请并授权发明专利10余件

10篇代表性论文：

Yiyan He, Yu Nie, Gang Cheng, Li Xie, Youqing Shen, Zhongwei Gu*, Viral mimicking ternary polyplexes: a reduction-controlled hierarchical unpacking vector for gene delivery; Advanced Materials 2014, 26: 1534-1540.

Yiyan He, Yu Nie*, Li Xie, Hongmei Song, Zhongwei Gu*, p53 mediated apoptosis by reduction sensitive shielding ternary complexes based on disulfide linked PEI ternary complexes; Biomaterials 2014, 35: 1657-1666.

Yiyan He, Gang Cheng, Li Xie, Yu Nie*, Bin He, Zhongwei Gu*, Polyethyleneimine/DNA polyplexes with reduction-sensitive hyaluronic acid derivatives shielding for targeted gene delivery; Biomaterials 2013, 34: 1235-1245.

Yiyan He, Jie Zhou, Shengnan Ma, Yu Nie, Dong Yue, Qian Jiang, Aisha Roshan Mohamed Wali, James Zhenggui Tang, Zhongwei Gu*. Multi-responsive "turn-on" nanocarriers for efficient site-specific gene delivery in vitro and in vivo. Advanced Healthcare Materials 2016, 5(21):2799-2812.

Jie Zhou#, Aisha Roshan Mohamed Wali#, Shengnan Ma, Yiyan He*, Dong Yue, James Zhenggui Tang, Zhongwei Gu*. Tailoring the Supramolecular Structure of Guanidinylated Pullulan toward Enhanced Genetic Photodynamic Therapy, Biomacromolecules 2018, 19(6):2214-2226.

Jie Zhou, Shengnan Ma, Yuxin Zhang, Yiyan He∗, Jun Yang, Hu Zhang, Kui Luo, Zhongwei Gu∗. Tunable membrane-penetrating bioreductive nanogels based on guanidinylated dendrimers for programmable gene delivery. Applied Materials Today 20 (2020) 100646.

Bo Yang, Jiliang Song, Yuhang Jiang, Ming Li, Jingjing Wei, Jiajun Qin, Wanjia Peng, Fernando López Lasaosa, Yiyan He*, Hongli Mao, Jun Yang, and Zhongwei Gu*, An Injectable Adhesive Self-healing Multi-cross-linked Double-network Hydrogel Facilitates Full-thickness Skin Wound Healing. ACS Applied Materials & Interfaces 2020, 12, 52, 57782-57797.

Jie Zhou, Shengnan Ma, Yuxin Zhang, Yiyan He*, Hongli Mao, Jun Yang, Hu Zhang, Kui Luo, Qiyong Gong, Zhongwei Gu*, Bacterium-mimicking sequentially targeted therapeutic nanocomplexes based on O-carboxymethyl chitosan and their cooperative therapy by dual-modality light manipulation. Carbohydrate Polymers 2021(264), 118030.

Yuhang Jiang, Wentao Zhao, Shuangshuang Xu, Jingjing Wei, Fernando López Lasaosa, Yiyan He*, Hongli Mao, Rosa María Bolea Bailo, Deling Kong, Zhongwei Gu*，Bioinspired design of mannose-decorated globular lysine dendrimers promotes diabetic wound healing by orchestrating appropriate macrophage polarization. Biomaterials 2022, 280, 121323.

Jiajun Qin, Ming Li, Ming Yuan, Xinglei Shi, Jiliang Song, Yiyan He*, Hongli Mao, Deling Kong, and Zhongwei Gu*, Gallium(III)-Mediated Dual-Cross-Linked Alginate Hydrogels with Antibacterial Properties for Promoting Infected Wound Healing. ACS Applied Materials & Interfaces 2022, 14, 19, 22426-22442.