姓名：Sanjiv Sharma

性别：男

职称/职务：授课教师-聚合物:性质与设计

网页: https://www.swansea.ac.uk/staff/sanjiv.sharma/

个人简介：

       Sanjiv Sharma博士于2001年获得博士学位，主要研究使用小型分离系统测定某些药物及其代谢物的分析方法。他的博士学位由Sunil Kumar Sanghi博士指导，是与阿姆斯特丹大学合作的印欧共同体小型分离系统联合研究项目的一部分。随后，他于2001年至2004年在法国和德国进行了高通量测序，临床蛋白质组学和小型化分析系统领域的博士后研究。2004年，他被授予志奋领技术奖学金，与伦敦帝国理工学院化学系的Andrew de Mello教授合作研究微流体微反应系统。

完成奖学金后，他加入了伦敦帝国理工学院生物医学工程研究所，与Tony Cass教授在生物纳米技术和生物传感器领域合作。在这里，他开发了微创微针，从光刻制造到高通量制造，将这些微针从实验室带到了临床。Sanjiv参与了NIHR（i4i）资助的研究项目，涉及健康志愿者和T1D参与者与著名内分泌学家临床医生的临床研究;德斯蒙德·约翰斯顿教授和尼克·奥利弗教授。他发表了50多篇研究文章，并在德国、英国和美国申请了专利。Sanjiv目前是斯旺西大学科学与工程学院生物医学工程项目主任。在斯旺西，他致力于聚合物微针的治疗药物输送和诊断（治疗诊断）应用。

教育背景：

                                                                 1998.09-2001.01      化学博士,先进材料加工研究所(AMPRI),前身为区域

                                                           究实验室,印度博帕尔

工作经历：

                                                                  2005.09-2011.08    伦敦帝国理工学院研究员

                                                                  2011.09-2017.09      伦敦帝国理工学院研究员

                                                                  2017.10-2022.09       斯旺西大学工程学院高级讲师

                                                                  2022.09月至今       斯旺西大学工程学院高级讲师

研究领域：

·微针

·微创传感器

·连续血糖监测

·连续乳糖监测

·间质治疗药物监测

代表性成果：

1.Rawson, T., Gowers, S., Freeman, D., Wilson, R., Sharma, S., Gilchrist, M., MacGowan, A., Lovering, A., Bayliss, M., Kyriakides, M., Georgiou, P., Cass, A., O'Hare, D., & Holmes, A. (2019). Microneedle biosensors for real-time, minimally invasive drug monitoring of phenoxymethylpenicillin: a first-in-human evaluation in healthy volunteers. The Lancet Digital Health, 1(7), e335-e343. https://doi.org/10.1016/s2589-7500(19)30131-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51460 http://dx.doi.org/10.1016/s2589-7500(19)30131-1

2.Bollella, P., Sharma, S., Cass, A., Tasca, F., & Antiochia, R. (2019). Minimally Invasive Glucose Monitoring Using a Highly Porous Gold Microneedles-Based Biosensor: Characterization and Application in Artificial Interstitial Fluid. Catalysts, 9(7), 580 https://doi.org/10.3390/catal9070580, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50906

3.Guy, O., Sharma, S., Howells, O., Rajendran, N., Mcintyre, S., Amini-Asl, S., Henri, P., Liu, Y., Guy, O., Cass, A., & Morris, M. (2019). Microneedle array‐based platforms for future theranostic applications. ChemBioChem https://doi.org/10.1002/cbic.201900112, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49693

4.Sharma, S. (2019). Recent Developments in Continuous Monitoring Diagnostics with Microneedle Arrays. In 7th International Conference on the Development of Biomedical Engineering in Vietnam (BME7)BME7 Conference. https://doi.org/10.1007/978-981-13-5859-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48663

5.Bollella, P., Sharma, S., Cass, A., & Antiochia, R. (2019). Minimally-invasive Microneedle-based Biosensor Array for Simultaneous Lactate and Glucose Monitoring in Artificial Interstitial Fluid. Electroanalysis, 31(2), 374-382. https://doi.org/10.1002/elan.201800630, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48159

6.Bollella, P., Sharma, S., Cass, A., & Antiochia, R. (2019). Microneedle-based biosensor for minimally-invasive lactate detection. Biosensors and Bioelectronics, 123, 152-159. https://doi.org/10.1016/j.bios.2018.08.010, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43849

7.Sharma, S., El-Laboudi, A., Reddy, M., Jugnee, N., Sivasubramaniyam, S., Sharkawy, M., Georgiou, P., Johnston, D., Oliver, N., & Cass, A. (2018). A pilot study in humans of microneedle sensor arrays for continuous glucose monitoring. Analytical Methods, 10(18), 2088-2095. https://doi.org/10.1039/C8AY00264A, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa39114

8.Rawson, T., O’Hare, D., Herrero, P., Sharma, S., Moore, L., Barra, E., Roberts, J., Gordon, A., Hope, W., Georgiou, P., Cass, A., Holmes, A., & Sharma, S. (2017). Delivering precision antimicrobial therapy through closed-loop control systems. Journal of Antimicrobial Chemotherapy https://doi.org/10.1093/jac/dkx458, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37320 https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkx458/4688914

9. Ghoreishizadeh, S., Zhang, X., Sharma, S., & Georgiou, P. (2017). Study of Electrochemical Impedance of a Continuous Glucose Monitoring Sensor and its Correlation with Sensor Performance. IEEE Sensors Letters, 1-1. https://doi.org/10.1109/LSENS.2017.2778248, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37061

10. Rawson, T., Sharma, S., Georgiou, P., Holmes, A., Cass, A., & O'Hare, D. (2017). Towards a minimally invasive device for beta-lactam monitoring in humans. Electrochemistry Communications, 82, 1-5. https://doi.org/10.1016/j.elecom.2017.07.011, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36437 https://spiral.imperial.ac.uk/handle/10044/1/52776