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Dr Sanjiv Sharma
阅读次数:     发布时间:2025-09-14

姓名:Dr Sanjiv Sharma

职位:现任课程负责人-聚合物:性能与设计

网页: https://www.swansea.ac.uk/staff/sanjiv.sharma/


个人简介:

       Sanjiv Sharma博士于2001年获得博士学位,研究方向是开发利用小型分离系统测定某些药物及其代谢物的分析方法。他的博士学位由Sunil Kumar Sanghi博士指导,是印欧共同体与阿姆斯特丹大学合作的小型分离系统联合研究项目的一部分。2001-2004年,他在法国和德国从事高通量测序、临床蛋白质组学和小型化分析系统领域的博士后研究。2004年,他在伦敦帝国理工学院化学系与Andrew deMello教授合作研究微流体微反应系统,获得Chevening技术奖学金。

在完成奖学金后,他加入了伦敦帝国理工学院生物医学工程研究所,与Tony Cass教授在生物纳米技术和生物传感器领域合作。在这里,他开发了微创微针,从光刻制造到高通量制造,将这些微针从实验室带到临床。Sanjiv参与了NIHR(i4i)资助的一项研究项目,该项目涉及与著名内分泌学家临床医生一起对健康志愿者和T1D患者进行临床研究;Desmond Johnston教授和Nick Oliver教授。他发表了50多篇研究论文,并在德国、英国和美国申请了专利。

Sanjiv目前是斯旺西大学科学与工程学院生物医学工程项目主任。在斯旺西,他正在研究治疗药物输送和聚合物微针的诊断(治疗)应用。


教育背景:

1998.09 – 2001.01化学博士,先进材料加工研究所(AMPRI),前身为区域研究实验室,博帕尔,印度


工作经历:

2022.09 – 至今项目主任,生物医学工程,斯旺西大学

2017.10 – 2022.09 高级讲师,工程学院,斯旺西大学

2011.09 – 2017.09研究员,伦敦帝国理工学院研究员

2005.09 – 2011.08研究人员,伦敦帝国理工学院研究员


研究领域:

微创微针

微创传感器

持续血糖监测(CGM)

持续乳酸监测(CLM)

间质治疗药物监测(iTDM)


代表性成果:

1. Rawson, T., Gowers, S., Freeman, D., Wilson, R., Sharma, S., Gilchrist, M., MacGowan, A., Lovering, A., Bayliss, M., Kyriakides, M., Georgiou, P., Cass, A., O'Hare, D., & Holmes, A. (2019). Microneedle biosensors for real-time, minimally invasive drug monitoring of phenoxymethylpenicillin: a first-in-human evaluation in healthy volunteers. The Lancet Digital Health, 1(7), e335-e343.

https://doi.org/10.1016/s2589-7500(19)30131-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51460

http://dx.doi.org/10.1016/s2589-7500(19)30131-1

2. Bollella, P., Sharma, S., Cass, A., Tasca, F., & Antiochia, R. (2019). Minimally Invasive Glucose Monitoring Using a Highly Porous Gold Microneedles-Based Biosensor: Characterization and Application in Artificial Interstitial Fluid. Catalysts, 9(7), 580

https://doi.org/10.3390/catal9070580, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50906

3. Guy, O., Sharma, S., Howells, O., Rajendran, N., Mcintyre, S., Amini-Asl, S., Henri, P., Liu, Y., Guy, O., Cass, A., & Morris, M. (2019). Microneedle array‐based platforms for future theranostic applications. ChemBioChem

https://doi.org/10.1002/cbic.201900112, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49693

4. Sharma, S. (2019). Recent Developments in Continuous Monitoring Diagnostics with Microneedle Arrays. In 7th International Conference on the Development of Biomedical Engineering in Vietnam (BME7)BME7 Conference.

https://doi.org/10.1007/978-981-13-5859-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48663

5. Bollella, P., Sharma, S., Cass, A., & Antiochia, R. (2019). Minimally-invasive Microneedle-based Biosensor Array for Simultaneous Lactate and Glucose Monitoring in Artificial Interstitial Fluid. Electroanalysis, 31(2), 374-382.

https://doi.org/10.1002/elan.201800630, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa48159

6. Bollella, P., Sharma, S., Cass, A., & Antiochia, R. (2019). Microneedle-based biosensor for minimally-invasive lactate detection. Biosensors and Bioelectronics, 123, 152-159.

https://doi.org/10.1016/j.bios.2018.08.010, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43849

7. Sharma, S., El-Laboudi, A., Reddy, M., Jugnee, N., Sivasubramaniyam, S., Sharkawy, M., Georgiou, P., Johnston, D., Oliver, N., & Cass, A. (2018). A pilot study in humans of microneedle sensor arrays for continuous glucose monitoring. Analytical Methods, 10(18), 2088-2095.

https://doi.org/10.1039/C8AY00264A, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa39114

8. Rawson, T., O’Hare, D., Herrero, P., Sharma, S., Moore, L., Barra, E., Roberts, J., Gordon, A., Hope, W., Georgiou, P., Cass, A., Holmes, A., & Sharma, S. (2017). Delivering precision antimicrobial therapy through closed-loop control systems. Journal of Antimicrobial Chemotherapy

https://doi.org/10.1093/jac/dkx458, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37320

https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkx458/4688914

9. Ghoreishizadeh, S., Zhang, X., Sharma, S., & Georgiou, P. (2017). Study of Electrochemical Impedance of a Continuous Glucose Monitoring Sensor and its Correlation with Sensor Performance. IEEE Sensors Letters, 1-1.

https://doi.org/10.1109/LSENS.2017.2778248, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37061